Contact your doctor if you have more than four headaches in one month 30 days. Tell your doctor if this medicine seems to stop working as well in treating your migraine attacks. Imitrex Injection should continue for at least 10 hours or while symptoms or signs persist. Loi V, Lai M, Pisano MR, Delzompo M "Sumatriptan and panic-like symptoms. Pale or blue-colored hands or feet. purchase generic bicalutamide mastercard europe
HGPRT assay. In 2 cytogenetics assays the in vitro human lymphocyte assay and the in vivo rat micronucleus assay sumatriptan was not associated with clastogenic activity. Remember, if you answered YES to any of the above questions, then discuss it with your doctor. Oral administration of sumatriptan to pregnant rabbits during the period of organogenesis resulted in increased incidences of embryolethality and fetal cervicothoracic vascular and skeletal abnormalities. Intravenous administration of sumatriptan to pregnant rabbits during the period of organogenesis resulted in an increased incidence of embryolethality.
This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use and wear protective clothing when outdoors. IMITREX Injection should not be given intravenously because of its potential to cause coronary vasospasm. Imitrex Injection is not indicated for the prevention of migraine or cluster headache attacks. Mild or flushing may occur. These effects are usually temporary and may disappear as your body adjusts to this product. If any of these effects persist or worsen, contact your doctor or promptly. This information should not be used to decide whether or not to take Imitrex tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Imitrex tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Imitrex tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Imitrex tablets.
IMITREX STATdose Pen, 2 prefilled single-dose syringe cartridges, and 1 carrying case NDC 0173-0739-00. Respiratory: Bronchospasm in patients with and without a history of asthma. You can buy some over the counter. But stronger NSAIDs need a prescription.
Cerebral hemorrhage, subarachnoid hemorrhage, and stroke have occurred with 5-HT1 treatment; some have resulted in fatalities. One case of sumatriptan-induced cortical stroke has been reported in a patient with sagittal sinus thrombosis. In some cases, it appears possible that the cerebrovascular events were primary, and the 5-HT1 agonist administered in the belief that presenting symptoms were due to migraine when they were not. Patients with migraine may also be at an increased risk of certain cerebrovascular events such as stroke, hemorrhage, and transient ischemic attacks. Pregnancy Category C: There are no adequate and well-controlled trials in pregnant women. In developmental toxicity studies in rats and rabbits, oral administration of sumatriptan to pregnant animals was associated with embryolethality, fetal abnormalities, and pup mortality. When administered by the intravenous route to pregnant rabbits, sumatriptan was embryolethal. Imitrex Tablets should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Ask your healthcare provider if you should take your first dose in a medical setting. The nerve that's affected, the trigeminal nerve, is responsible for sensations such as heat or pain in your face. Breasts: Breast swelling, cysts, disorder of breasts, lumps, masses of breasts, nipple discharge, primary malignant breast neoplasm, and tenderness. Eye: Infrequent were irritation of eyes and visual disturbance. Dihydroergotamine can be effective in some people who do not get relief from triptans. Imitrex can cause dizziness, weakness, or drowsiness. If you have these symptoms, do not drive a car, use machinery, or do anything where you need to be alert. You get a cluster headache when a specific nerve pathway in the base of your is activated. That signal seems to come from a deeper part of the called the hypothalamus, where the "internal biological clock" that controls your and wake cycles lives. Number of headaches treated. The pharmacokinetics of sumatriptan in the elderly mean age: 72 years, 2 males and 4 females and in subjects with migraine mean age: 38 years, 25 males and 155 females were similar to that in healthy male subjects mean age: 30 years. Seizures have happened in people taking Imitrex who have never had seizures before. Talk with your healthcare provider about your chance of having seizures while you take Imitrex.
Pediatric Use: Safety and effectiveness of IMITREX Injection in pediatric patients under 18 years of age have not been established; therefore, IMITREX Injection is not recommended for use in patients under 18 years of age. For adults, the usual dose is a single injection given just below the skin. It should be given as soon as the symptoms of your migraine appear, but it may be given at any time during an attack. A second injection may be given if your symptoms of migraine come back. If your symptoms do not improve following the first injection, do not give a second injection for the same attack without first consulting with your doctor. Do not have more than 2 injections in any 24 hours and allow at least 1 hour between each dose. There are no adequate and well-controlled trials of Imitrex Injection in pregnant women. In developmental toxicity studies in rats and rabbits, oral administration of sumatriptan to pregnant animals was associated with embryolethality, fetal abnormalities, and pup mortality. When administered by the intravenous route to pregnant rabbits, sumatriptan was embryolethal. Imitrex Injection should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Have you ever had to stop taking this or any other medicine because of an allergy or other problems? USP in Water for Injection, USP. RxList is part of the WebMD Health Network. The opinions expressed in the WebMD User Reviews are solely those of the User, who may or may not have medical or scientific training, and do not represent the opinions of WebMD. These member reviews have not been reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other purpose except for compliance with our Terms and Conditions. cefpodoxime
Always consult a healthcare professional for medical advice. If some response to first dose occurs, a second dose may be administered at least 1 hour after first dose if needed. Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. Lab tests, including heart function tests, may be performed while you use Imitrex spray. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. What are the ingredients in IMITREX Injection? If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Ottervanger JP, van Witsen TB, Valkenburg HA, Stricker BH "Postmarketing study of cardiovascular adverse reactions associated with sumatriptan. Cmax and AUC were increased by 15% and 12%, respectively, when administered in the fed state. Different brands of this medication have different storage needs. Check the product package for instructions on how to store your brand, or ask your pharmacist. Do not store in the bathroom. Do not discard the auto-injector. You may use it again with refills of the prefilled syringes. However, if you are using a one-time use auto-injector, discard the auto-injector after use. If you are unsure if your auto-injector can be re-used, ask your pharmacist. Keep all medicines away from children and pets. cebep.info erythromycin
Trials 1, 2, and 3 following administration of Imitrex Tablets compared with placebo. This medication may also be used as a backup for sumatriptan injection. If your symptoms are only partly relieved or your headache comes back, you may take a dose of sumatriptan by mouth at least two hours after the injection, up to a maximum of 100 milligrams in a 24-hour period. How should I store IMITREX Injection? Dachs R, Vitillo J "Angioedema associated with sumatriptan administration. If your medicine has expired the expiration date is printed on the treatment pack throw it away as instructed. Do not throw away your autoinjector. Respiratory Rate: Experience gained during the clinical development of sumatriptan as a treatment for migraine failed to detect an effect of the drug on respiratory rate. Is this headache different from your usual migraine attacks? IMITREX Injection is indicated for 1 the acute treatment of migraine attacks with or without aura and 2 the acute treatment of cluster headache episodes. Do not use more than the amount prescribed by your doctor in a 24-hour period or treat more than 4 headaches within 30 days without checking with your doctor. The abuse potential of IMITREX Injection cannot be fully delineated in advance of extensive marketing experience. It may harm them. When nothing else has worked, surgery may be an option for people who don't get a break from cluster headaches. Most of the procedures involve blocking the trigeminal nerve. You tend to get them at the same time each year, such as the spring or fall. Because of their seasonal nature, people often mistake for or business stress. cheapest paroxetine purchase now mastercard
When your sharps disposal container is almost full, you will need to follow your community guidelines for the right way to dispose of your sharps disposal container. There may be state or local laws about how you should throw away used needles and cartridges. After using the nasal spray: If your headache does not completely go away, call your doctor before using a second spray of sumatriptan. If your headache goes away and then comes back, you may use a second spray if it has been at least 2 hours since you used the first spray. Do not use more than 40 mg of sumatriptan nasal spray in 24 hours. If your symptoms do not improve, contact your doctor before using any more sprays. Anti-nausea medications. These drugs may help you absorb your pain medication. The following adverse reactions have been identified during postapproval use of Imitrex Tablets, Imitrex Nasal Spray, and Imitrex Injection. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. These reactions have been chosen for inclusion due to either their seriousness, frequency of reporting, or causal connection to Imitrex or a combination of these factors. If you are at high risk for heart disease, your doctor may want to check your heart before prescribing sumatriptan. Each tablet contains sumatriptan succinate equivalent to 25 mg of sumatriptan. If migraine returns after an initial dose of subcutaneous injection, additional oral doses may be given up to 100 mg orally per day, with at least a 2 hour interval between tablet doses. Chiropractic and osteopathy. When causes tension headaches, a may be able to ease it with spinal or cervical manipulation and realignment. The safety of treating an average of more than 4 headaches in a 30-day period has not been established. Patients who are advised to self-administer IMITREX Injection in medically unsupervised situations should receive instruction on the proper use of the product from the physician or other suitably qualified health care professional prior to doing so for the first time. Be sure to write down all your important numbers and keep them in a safe place. What are the possible side effects of IMITREX? Serotonin syndrome is a possibly fatal syndrome that can be caused by Imitrex spray. Your risk may be greater if you take Imitrex spray with certain other medicines eg, SSRIs, SNRIs. Symptoms may include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact your doctor at once if you have any of these symptoms. Treatment for these health problems also may help you have fewer headaches. buy azelastine drug
Severe and sometimes fatal allergic reactions have rarely happened. Discuss any questions or concerns with your doctor. Injection is contraindicated in patients with a history of stroke or TIA. Seizures have been reported in patients with either a history of seizures or concurrent conditions predisposing to seizures and also in patients where no such predisposing factors are apparent. There may be new information. Techniques to stop negative thoughts.
Use Imitrex tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions. My doctor tells me my body couldn't handle the return to normal food, and reacted with the diarrhea and subsequent headaches. Read the Patient Information Leaflet available from your before you start using and each time you get a refill. Ask your doctor or pharmacist if you have any questions. Food and Drug Administration. WebMD does not endorse any specific product, service or treatment. Treatment of migraine attacks with sumatriptan. the subcutaneous sumatriptan international study group. Sumatriptan is a headache medicine that narrows blood vessels around the brain. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms. IMITREX may cause serious side effects. Store your medicine away from light. loratadine
IMITREX. Such reactions can be life threatening or fatal. In general, anaphylactic reactions to drugs are more likely to occur in individuals with a history of sensitivity to multiple allergens. Imitrex Injection is contraindicated in patients with a history of hypersensitivity reaction to IMITREX. Reports of transient and permanent blindness and significant partial vision loss have been reported with the use of 5-HT 1 agonists. Since visual disorders may be part of a migraine attack, a causal relationship between these events and the use of 5-HT 1 agonists have not been clearly established. MAO-A inhibitor on the bioavailability from a 25-mg oral sumatriptan tablet resulted in an approximately 7-fold increase in systemic exposure. IMITREX Injection 1 hour after the initial injection. But these medicines may not be as effective as other medicines, such as triptans. Inject with the IMITREX STAT dose Pen. Imitrex Tablets. Such reactions can be life threatening or fatal. Learn all preparation and usage instructions in the product package. If any of the information is unclear, consult your doctor or pharmacist. Make sure you understand the correct technique for injection and how to properly dispose of needles, syringes, auto-injectors, needle-free devices, and unused medication. It is unknown if this drug passes into milk. Consult your doctor before -feeding. IMITREX is not used to prevent or decrease the number of migraine or cluster headaches you have. Sensations of tightness, pain, pressure, and heaviness in the precordium, throat, neck, and jaw commonly occur after treatment with Imitrex Tablets and are usually non-cardiac in origin. However, perform a cardiac evaluation if these patients are at high cardiac risk. order now kemadrin from pharmacy
Not applicable. See How to Use section. TIA. Discontinue Imitrex Injection if a cerebrovascular event occurs. Imitrex tablets should not be used to prevent or reduce the number of migraine headaches you have. If you have a headache that is different than your usual migraine headaches, check with your doctor before using Imitrex tablets. Sumatriptan can pass into breast milk and may harm a nursing baby. Do not breast-feed within 12 hours after using sumatriptan. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; bloody diarrhea; burning or aching in your feet or toes; burning, numbness, or tingling; constipation; diarrhea; fainting; feeling of heaviness or tightness in your leg muscles; fever; hearing problems; leg cramps; seizures; severe or persistent headache, dizziness, nausea, or vomiting; severe stomach pain; very cold or blue fingers or toes; vision changes or loss of vision; weight loss; wheezing. This medication may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Endocrine and Metabolic: Elevated thyrotropin stimulating hormone TSH levels; endocrine cysts, lumps, and masses; fluid disturbances; galactorrhea; hyperglycemia; hypoglycemia; hypothyroidism; weight gain; and weight loss. When did your headaches first start? How should I store Imitrex Injection? BM, but not one that wouldn't go away within 15-20 mins after. It was a 10 out of 10 pain and I was wailing in pain and could not just stay in a dark room and try and sleep it out. I had my Mom come check on me and she looked up this page and read your post, which told us that hopefully it was just a very very intense migraine, but just be be sure we called my doctor and he instructed us to call the ambulance. IMITREX is not for people with risk factors for heart disease unless a heart exam is done and shows no problem. Meds that can ease migraine pain as it's happening are called “acute” treatments. The effect of sumatriptan on the protein binding of other drugs has not been evaluated. Put the Pen in the open Cartridge Pack. cheap zyloprim online australia
Drowsiness may occur during a migraine or during its treatment with this drug. Do not drive or operate machinery until you know how this drug affects you. Musculoskeletal: Infrequent were various joint disturbances pain, stiffness, swelling, ache. Rare were muscle stiffness, need to flex calf muscles, backache, muscle tiredness, and swelling of the extremities. The pharmacokinetics of sumatriptan in patients with severe hepatic impairment has not been studied. What are the ingredients in Imitrex Tablets? The risk of heart disease, liver disease, and high blood pressure increases with age. Older adults may be more sensitive to the side effects of this drug, especially increased blood pressure and heart problems. Imitrex passes into your breast milk and may harm your baby. Talk with your healthcare provider about the best way to feed your baby if you take Imitrex. Take this medication only as needed when a migraine occurs, as directed by your doctor. This medication should not be taken on a regular schedule. Never increase your dose of this medication or take it more often than prescribed by your doctor. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Sumatriptan injection is not approved for use by anyone younger than 18 years old. Carrying Case for your convenience. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Triptans work best if you take them within 2 hours of the start of your pain. cefadroxil
Priming Rod does not stick out and to get the Pen ready for the next use. IMITREX Injection, 0% placebo. Retrace your steps if you can't remember why you went into a room. This may not be a complete list of all interactions that may occur. Ask your health care provider if Imitrex spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. One report has suggested that "throat tightness" and chest pain associated with sumatriptan may sometimes be attributable to changes in esophageal motility. Sumatriptan may also be used for purposes not listed in this medication guide. What is the most important information I should know about sumatriptan? Keep all regular medical and laboratory appointments. The effect of mild to moderate hepatic disease on the pharmacokinetics of subcutaneously administered sumatriptan has been evaluated. There were no significant differences in the pharmacokinetics of subcutaneously administered sumatriptan in moderately hepatically impaired subjects compared with healthy controls. The pharmacokinetics of subcutaneously administered sumatriptan in patients with severe hepatic impairment has not been studied. Ways to manage your time. This drug passes into breast milk in small amounts. Consult your doctor before breast-feeding.
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Two studies published in the Nov. 7 advance online edition of the Annals of Neurology suggest that the success of migraine treatment with triptans is related to the skin sensitivity symptom commonly found in migraine sufferers. This symptom, known as cutaneous allodynia, occurs in about three-fourths of migraine suffers and frequently affects the skin of the face and neck, making even mundane activities like brushing one's or shaving extremely painful. Overuse of drugs to treat sudden migraine attacks can lead to worsening of headache medication overuse headache or rebound headache. Therefore, do not use this medication more often or for longer than prescribed. Tell your doctor if you need to use this medication more often, if the medication is not working as well, or if you have more frequent or worse headaches.
Preventive medicines often work when you take them at the first sign of a new cluster of headaches. IMITREX Injection or Tablets. Gastrointestinal: Ischemic colitis with rectal bleeding see xerostomia.
About FAERS: The FDA Adverse Event Reporting System FAERS is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. Some medical conditions may interact with Imitrex spray. Cartridge Pack out of the Carrying Case.
Do you have risk factors for heart disease such as high blood pressure, high cholesterol, obesity, diabetes, smoking, strong family history of heart disease, or you are postmenopausal or a male over 40? IAA or the IAA glucuronide, both of which are inactive. Plot. Patients taking rescue medication were censored at 15 minutes. Do you have any symptoms before the headache starts? IMITREX Injection is intended to relieve your migraine or cluster headache, but not to prevent or reduce the number of attacks you experience. Use IMITREX Injection only to treat an actual migraine or cluster headache attack.